Relaying what matters next.

Three credible trials are dragging senolytics out of mouse lore and into human data. St. Jude pits dasatinib plus quercetin against fisetin, Washington University runs SToMP-AD in early Alzheimer’s, and NIH backs a frailty study in people aging with HIV. Intermittent pulse dosing, functional endpoints like gait speed, and on-target biomarkers could make 2025 the pivot year.

With Solar Cycle 25 surging, NASA’s IMAP heads for the Sun-Earth L1 point to image the heliosphere in 3D while SWFO‑L1 delivers earlier, more reliable space weather alerts.

OpenAI has folded its Operator browser agent into ChatGPT and is steering the stack toward supervised cloud workers. Here is what cloud‑scale agents mean for SaaS vendors, enterprise IT, and developers, plus a practical checklist to get ready.

On September 15 the U.S. Army brought its Typhon mid range missile system to MCAS Iwakuni for Resolute Dragon, putting land based SM 6 and Tomahawk options back inside the First Island Chain. The short stay signals a durable shift in Indo Pacific deterrence rather than a one off showcase.

Telegram is rolling out a self-custodial TON Wallet for U.S. users, bringing USDT payments, swaps, and mini-apps into the chat interface. Here is what it unlocks for payments, games, and developers.

U.S. grid operators just opened express lanes for near‑term megawatts. We break down which PJM, MISO and CAISO projects can realistically hit 2027 to 2029 CODs, how PJM’s record capacity prices tilt technology choices, and the moves developers, LSEs and data centers should make now.

With the FDA’s first efficacy green light for a canine anti aging pill and a revived NIH backed rapamycin trial, companion dogs are becoming the de risked bridge to human geroprotectors. Here is the biology, the regulatory playbook, and what to watch next.

NASA confirmed on January 28, 2025 that Juno’s December 27, 2024 flyby of Io recorded the moon’s most energetic volcanic outburst yet. A giant southern hotspot and nearby sites brightened together, pointing to connected magma reservoirs and a rethink of how tidal heating works.

Workday is buying Sana for $1.1 billion and turning HR and finance into the default home for enterprise AI agents. Here is why a front door inside Workday could reshape governance, buying centers, and the next wave of startup opportunities.

YFQ-42A’s first flight and official fighter-series designations mark the moment CCAs left the slide deck and entered combat reality. Here is how autonomy, jamming resilience, modular payloads, and budgets will reshape air dominance.

Custodial exchanges, hosted wallets, and payment processors are brokers in 2025. Expect 1099-DA for gross proceeds in early 2026, with basis reporting starting in 2026. DeFi front ends and self-custody remain outside broker rules after Congress repealed the late-2024 DeFi measure.

State primacy over Class VI wells and the first Gulf Coast permits are finally moving U.S. CCS from proposals to construction. Texas and Appalachia are speeding up while tougher pipeline standards may decide who reaches financing and rights of way first.

A March 31, 2025 court decision vacated FDA’s LDT rule. On September 19, 2025, FDA formally rescinded it, putting aging tests back under CLIA and shifting the strategy for endpoints, payers, and trial design.

China’s Tianwen-2 is chasing Earth’s tiny quasi-moon Kamoʻoalewa for a bold sample return, with a 2027 drop-off and a follow-on cruise to 311P. The payoff spans lunar history and real-world planetary defense.

CrowdStrike’s plan to acquire Pangea puts AI Detection and Response on the map. Here is why agentic systems need their own security stack, how to stop agent hijacking and shadow AI, and what builders and CISOs should operationalize next.

Washington just turned Golden Dome from talking point into a program with dates, orbits, and dollars. We map the physics, constellation math, budget risks, and what is actually realistic by 2029.

Uniswap’s Unichain has switched on 200 ms Flashblocks. By pairing fee-first ordering inside a trusted execution environment with an encrypted mempool, it promises near‑instant preconfirmations, less extractive MEV, and a cleaner trading experience. Here is what changes for traders, LPs, and builders.

June 24 changed the U.S. solar market. Antidumping and countervailing duty orders on four Southeast Asian countries bent the price curve, and fresh probes into India, Laos, and Indonesia could force another pivot before year end. Here is what it means for sourcing, PPAs, and schedules.