Relaying what matters next.

In 2025, lipoprotein(a) finally became actionable. Durable RNA silencers cut Lp(a) 80 to 95 percent and an oral blocker emerged, setting up twice-yearly injections or a daily pill as a new backbone for cardiovascular prevention.

Q4 2025 turns agent memory into the new battleground. Platforms now ship project and team memory, vector-native storage, and consent policies that lock in context. Here is the emerging stack, the tradeoffs, and a portable blueprint to ship.

Starknet has switched on BTCFi, bringing non-custodial Bitcoin staking and a 100 million STRK incentive program to jump-start BTC-backed lending and liquidity. Here is what launched, how it works, the risks, and the scorecard to watch over the next six months.

NASA has funded two rival paths to land a Mars Ascent Vehicle and bring Perseverance’s samples home. Lock the right interfaces in 2025, hold the 2026 downselect, and Earth could see Mars rocks in the mid‑2030s. Slip again, and China may claim first return.

Moderna’s cytomegalovirus vaccine is nearing a pivotal 2025 efficacy readout that could recast prevention as a lever on immune aging. Here is what matters for regulators, payers, and anyone tracking the first real test of longevity vaccines.

In July 2025 regulators opened the gate for Palisades, the first U.S. commercial reactor moving from retirement back to operation. This roadmap shows how NRC approvals, DOE financing, and a contract-led model can be replicated at other brownfield sites.

A rare SEC-CFTC joint signal just opened the door for registered US exchanges to list certain spot crypto products. Here is what surveillance, custody, cross margin, fees, and a 3 to 12 month rollout could look like, plus who moves first.

Perplexity just unlocked Comet for everyone, signaling a shift from chat windows to the place work actually happens: your browser. Here is why the browser will beat chat apps as the agent runtime, how Comet stacks up against Gemini in Chrome, Arc’s Dia, and Opera’s Neon, and what builders should ship next.

DBS will list Franklin Templeton’s sgBENJI on the XRP Ledger alongside Ripple’s RLUSD stablecoin, giving accredited and institutional clients a regulated way to trade, pledge and sweep cash into a yield‑bearing fund with on‑ledger settlement and bank‑grade controls.

IRS and Treasury s January 2025 decision turned 45V from debate into deal math: annual matching through 2029, hourly by 2030; deliverability by DOE grid regions; new incrementality including at-risk nuclear; and tracked RNG and coal-mine methane starting in 2027. This guide translates rules into siting and contracting moves.

NASA has brought VIPER back by tasking Blue Origin to prepare a 2027 south pole delivery. The option depends on Blue Moon MK1 completing its first landing later in 2025, a pivotal test for lunar logistics.

On September 1, 2025, Tether ended support for five legacy networks and pushed USDT flows to a few dominant rails. Here is what changed, who benefits, and how teams should migrate without breaking payments.

Agent observability just moved from slideware to shipped software. With OpenTelemetry traces, Model Context Protocol, and real-time dashboards, enterprises can turn experimental agents into governed, measurable systems and prove ROI through 2026.

On October 3, 2025, the interstellar comet 3I/ATLAS makes a rare pass by Mars. Here is what telescopes are racing to learn now—and the four concrete steps space agencies should lock in before the next one appears.

With LNG export reviews back on track in January 2025, Gulf Coast projects and supply chains have shifted from pause to push. Here’s how fresh approvals reshape 2030 capacity, pricing risk, bunkering, and who advances next.

Fresh ESC 2025 data suggest that daily low-dose colchicine slows the growth of TET2-driven clonal hematopoiesis, an age-linked blood clone tied to cardiovascular and cancer risk. Here is a practical case for midlife CHIP screening and a near-term path to clone-targeted therapies.

At Sibos 2025 in Frankfurt, a production workflow from Swift, DTCC and Chainlink standardizes corporate actions into on chain golden records mapped to ISO 20022. The result is faster timelines, fewer breaks and a clear path to tokenized funds at scale.

The Ethereum Foundation set a one-year target to bring L1 zkEVM online, starting with optional proof verification on mainnet. Here is what real-time proving, multi-proof clients, and native zk-rollups could mean for gas limits, MEV, and every L2 team.